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PHENYLTHIOHYDANTOIN-TRYPTOPHAN

  • CAS No.: 5789-24-2
  • Purity: 99%
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Manufacturer supply high quality PHENYLTHIOHYDANTOIN-TRYPTOPHAN 5789-24-2 with ISO standards

  • Molecular Formula: C18H15 N3 O S
  • Molecular Weight: 321.403
  • Vapor Pressure: 7.95E-11mmHg at 25°C 
  • Melting Point: 183 °C 
  • Boiling Point: 538.8°Cat760mmHg 
  • PKA: 11.12±0.40(Predicted) 
  • Flash Point: 236.1°C 
  • PSA: 80.22000 
  • Density: 1.156g/cm3 
  • LogP: 3.39410 

PHENYLTHIOHYDANTOIN-TRYPTOPHAN(Cas 5789-24-2) Usage

General Description

Phenylthiohydantoin-tryptophan is a chemical compound used in the process of sequencing proteins. It is formed by the reaction of phenylisothiocyanate with tryptophan, resulting in the formation of a phenylthiohydantoin derivative of tryptophan. PHENYLTHIOHYDANTOIN-TRYPTOPHAN is used in the Edman degradation method, a technique for determining the sequence of amino acids in a protein. It works by cleaving the N-terminal amino acid and converting it into a derivative that can be identified and analyzed. Phenylthiohydantoin-tryptophan plays a crucial role in protein sequencing and has applications in biochemistry and pharmaceutical research.

InChI:InChI=1/C18H15N3OS/c22-17-16(10-12-11-19-15-9-5-4-8-14(12)15)20-18(23)21(17)13-6-2-1-3-7-13/h1-9,11,16,19H,10H2,(H,20,23)

5789-24-2 Process route

phenyl isothiocyanate
103-72-0

phenyl isothiocyanate

Trp
54-12-6,27732-43-0,80206-30-0,27813-82-7

Trp

D,L-trypthphan N-phenylthiohydantoin
5789-24-2

D,L-trypthphan N-phenylthiohydantoin

Conditions
Conditions Yield
With pyridine; sodium hydroxide; anschliessend Erwaermen des Reaktionsprodukts mit Essigsaeure;
D,L-trypthphan N-phenylthiohydantoin
5789-24-2

D,L-trypthphan N-phenylthiohydantoin

Conditions
Conditions Yield
C6H5NiCS 1) L-Tryptophan, ethanol. KOH, 20grad 2) Eg., 40grad;
(yield)62percent;

5789-24-2 Upstream products

  • 103-72-0
    103-72-0

    phenyl isothiocyanate

  • 54-12-6
    54-12-6

    Trp

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